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Int J Environ Res Public Health, 2011
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Images Overview thyroid hormone synthesis two forms (T 3 and T 4 ) T 3 is more potent than T 4 rT 3 is inactive contain iodine transported in blood bound to thyroxine-binding globulin (TBG) Function bone growth CNS maturation recall cretinism involves short stature and mental retardation increase the basal metabolic rate via ↑ Na + /K + -ATPase activity results in ↑ O2 consumption, RR, and body temperature ↑ β 1 receptors in heart results in ↑ CO, HR, SV, and contractility ↑ glycogenolysis, gluconeogenesis, and lipolysis created in the thyroid gland stored in thyroid follicles thyroid peroxidase responsible for oxidation, organification, and coupling forms I 2 via oxidation of I- forms thyroglobulin via organification of I 2 T 4 converted to T 3 in peripheral tissues by outer ring deiodinase T 4 converted to rT 3 by inner ring deiodinase Regulation TRH released from the hypothalamus to stimulates TSH release from the pituitary TSH stimulates follicular cells to produce T 3 and T 4 Create a free account or log in to see the cards.