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Because glutathione plays so many roles, the symptoms tend to be broad rather than specific, which is part of why it often goes overlooked: Persistent fatigue or low energy that doesn’t resolve with rest 1 Brain fog, poor concentration, or memory issues 2 Frequent illness or slow recovery from infections 3 Anxiety, low mood, or depression 4 Joint pain or general inflammation Sluggish detoxification (sensitivity to alcohol, chemicals, or medications) 5 Slower recovery after exercise 6 If several of these resonate, optimizing glutathione (starting with food) is a reasonable place to focus
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Inhibitors 6 - 8 were incubated with TGR with and without NADPH, and the inhibition of TGR activity was determined after adding a second aliquot of NADPH and 5,5’-dithiobis (2-nitrobenzoic acid) (DTNB)