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The oxidative stress markers, including MDA levels and the activities of antioxidant enzymes (GST, CAT and SOD), and non-enzymatic antioxidants (GSH and AA) were significantly altered in the PE-MP group

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For cases that are extensive or unresponsive yet stable, transplantation surgery may be considered, while Janus kinase inhibitors are an emerging option with promising trial results [199,200,201]